After a near-death experience during a strange tornado, Danielle Moonstar awakens in an abandoned research facility run by the mysterious Dr. Cecilia Reyes. There, Dr. Reyes introduces Dani to four other equally uncommon teenagers: Illyana Rasputin, Rahne Sinclair, Sam Guthrie, and Roberto da Costa, whom Dr. Reyes wants to keep safe and sound until they learn how to be in full control of their extraordinary abilities. However, even though the exceptional team of traumatized inmates believes that they're being treated and cared for, before long, they all start to experience horrifying hallucinations. Then they start to question if Dr. Reyes is telling them the truth about the purpose of their imprisonment.